Sodium tanshinone IIA sulfonate mediates electron transfer reaction in rat heart mitochondria

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Sodium tanshinone IIA sulfonate mediates electron transfer reaction in rat heart mitochondria.

In this paper, an electron transfer reaction mediated by sodium tanshinone IIA sulfonate (STS) was studied in rat heart mitochondria. It was found that STS could stimulate mitochondrial NADH oxidation dose-dependently and partly restore NADH oxidation in the presence of respiratory inhibitor (rotenone or antimycin A or KCN). It was likely that STS could accept electrons from complex I similar t...

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ژورنال

عنوان ژورنال: Biochemical Pharmacology

سال: 2003

ISSN: 0006-2952

DOI: 10.1016/s0006-2952(02)01447-8